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In double the recommended daily dose ursodeoxycholic acid reduces elevated liver enzyme levels in those with primary sclerosing cholangitis, but its use was associated with an increased risk of serious adverse events (the development of cirrhosis, varices, death or liver transplantation) in patients who received ursodeoxycholic acid compared with those who received placebo.

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Two patients in group A reported insomnia and edema of the lower limbs respectively, which resolved after reducing the celecoxib dose to halve the standard trial dose.

The purpose of this study was to determine the bioequivalence of four preparations of ursodeoxycholic acid (UDCA), which is currently the drug of choice for dissolving of cholesterol gallstones, and the probable drug of choice for chronic cholestatic liver disease, especially primary biliary cirrhosis.

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Drug induced fatty liver is characterized by mild to moderate serum enzyme elevations, generally with a hepatocellular pattern arising in a patient with fatty liver, as shown by liver biopsy or imaging tests, usually ultrasound.

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Doctor Xing-Qiang Wang said that it is better to tell them some basic information about the patient, for example, the age.

Ursodiol (also known as ursodeoxycholic acid, and sometimes abbreviated "URSO" or "UDCA") is a bile acid originally identified in bear bile.

My ultrasound report showed of mild hepato-splenomegaly and since i had a history of jaundice the doctor asked to have a SGPT test, which showed 132 on report.

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The percentage of a dose of intravenous flucloxacillin recovered in urine in an 8 hour collection period varies from 60 to 76%.

Patients with primary biliary cirrhosis when taking medication is sometimes noted deterioration of general condition, which stabilized after drug withdrawal.

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This may result in QT prolongation and cardiac arrhythmias including ventricular tachycardia, ventricular fibrillation and Torsade de Pointes.

Contact your doctor for instructions.

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Some antacid preparations contain aluminium salts which can interfere with the way ursodeoxycholic acid works.

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FAP familial adenomatous polyposis, APC adenomatous polyposis coli, CR colorectal, IRA ileorectal anastomosism, IPAA ileal pouch-anal anastomosis; Ileostomy: proctocolectomy with ileostomy, UDCA ursodeoxycholic acid, AMC Academic Medical Centre Amsterdam, EMC Erasmus Medical Centre Rotterdam, LUMC Leiden University Medical Centre, RUNMC Radboud University Nijmegen Medical Centre, UMCG University Medical Centre Groningen.

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Moreover, the trend of progressively increasing success with ursodiol after lithotripsy suggests that continued treatment with ursodiol beyond six months would yield further success.

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Cochrane review looking at primary biliary cirrhosis found that although ursodeoxycholic acid showed a reduction in liver biochemistry, jaundice, and ascites, it did not decrease mortality or liver transplantation.

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We found that addition of UDCA did not promote or retard the vascular shutdown associated with PDT at either SnET2 dose.

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The follow-up consists of 4 MRI controls of the abdomen using the hepatocyte-specific contrast agent Gd-EOB-DTPA (Primovist) after 3 days, 6 weeks, 3 months and 6 months as well as blood samples and a questionnaire taken the same time.

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The cytoprotective effect is based on the ability of ursodeoxycholic acid incorporated into the lipid layer of the cell membrane, which leads to stabilization of the cell membrane and improve its protective properties.

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Improvement of biliary enzyme levels and itching as a result of long-term administration of ursodeoxycholic acid in primary biliary cirrhosis.

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